News | Graduate School of Medical Sciences

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Cancer Progression Illuminated by New Multi-Omics Tool

A new tool developed by Weill Cornell Medicine and the University of Adelaide investigators has enhanced the ability to track multiple gene mutations while simultaneously recording gene activity in individual cancer cells. The technology, which can now use diverse types of pathology samples and quickly process large numbers of cells, has enabled the investigators to glean new insights into how cancers evolve toward greater aggressiveness and therapy resistance.

Dr...

Study Finds Restoring Order to Dividing Cancer Cells May Prevent Metastasis

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest to treat breast cancers, but a new study led by Weill Cornell Medicine suggests a way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs. The preclinical study also found drugs that block EZH2 could restore order to dividing cells and thwart the spread of TNBC cells.

“Metastasis is the main...

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NIH Grant Will Fund Autism Research Replication, Validation, and Reproducibility Center

Investigators at Weill Cornell Medicine and Cornell’s Ithaca campus have received a $5.1 million, three-year grant from the National Institutes of Health’s Autism Data Science Initiative (ADSI) to launch the Autism Replication, Validation, and Reproducibility (AR²) Center. The center aims to improve the reliability of autism research and foster public trust in the field.

Dr. Judy Zhong

“The AR² Center will serve as a...

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NIH Funds Study of Type 1 Diabetes Development

Weill Cornell Medicine has received a four-year, $3.4 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, for a study of the details and dynamics of the autoimmune process that causes type 1 diabetes. Dr. Shuibing Chen, the Kilts Family Professor of Surgery and director of the Center for Genomic Health at Weill Cornell Medicine, will lead the project. Dr. Chen’s long-time collaborator, Dr. Stephen Parker,...

Inflammation During Pregnancy May Prime Offspring for Anxiety

Increased risk for anxiety may begin before birth, shaped by infection or stressful events during pregnancy, according to a new preclinical study from researchers at Weill Cornell Medicine. While scientists have long known that maternal difficulty during pregnancy may raise a child’s risk for psychiatric illness, the biological pathways between these prenatal experiences and later mental health have been unclear.

The study, published Sept. 10 in Cell Reports, focuses on a region of the...

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Weill Cornell Doctoral Student Selected for HHMI Fellows Program

Weill Cornell Graduate School of Medical Sciences doctoral student Ana Campos Codo has been selected for the 2025 cohort of the Gilliam Fellows Program by Howard Hughes Medical Institute (HHMI).

Codo, a student in the Immunology and Microbial Pathogenesis Ph.D. program, is one of 30 graduate students representing 23 different institutions across the United States who were chosen this year. The 21-year-old Gilliam Fellows program, which launches...

The Quest for an HIV Vaccine

When SARS-CoV-2, the coronavirus that causes COVID-19, began spreading worldwide in 2020, many research teams immediately set to work developing a vaccine against it. Building on decades of previous work on mRNA technology and on other viral vaccines, including HIV, they achieved their goal within the year. The most widely used mRNA vaccine design contains the genetic instructions for the body to make the spike protein that the virus uses to enter cells. The resulting immune response...

Gut Neurons Help the Body Fight Inflammation

Neurons in the gut produce a molecule that plays a pivotal role in shaping the gut’s immune response during and after inflammation, according to a new study by Weill Cornell Medicine investigators. The findings suggest that targeting these neurons and the molecules they produce could open the door to new treatments for inflammatory bowel disease and other disorders driven by gut inflammation.

Hundreds of millions of neurons make up the enteric nervous system, the “second brain” of the...

Two Weill Cornell Medicine Scientists Selected for 2025 Pew Awards

Weill Cornell Medicine faculty member Dr. Anna Nam and postdoctoral fellow Dr. Maria Cecilia Lira have been chosen to join the 2025 class of Pew scholars and fellows.

Dr. Nam, an assistant professor of pathology and laboratory medicine at Weill Cornell Medicine, has been selected as a 2025 Pew-Stewart Scholar for Cancer Research. Now in its 12th year, the award, emanating from a partnership between The Pew Charitable Trusts and the Alexander and Margaret Stewart Trust, supports early...

Uncovering How a Molecule Responsible for Immune “Brakes” Directs Skin Defenses

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin. Early during infection, PD-1 acts like a steering wheel, guiding T cells to become protective resident memory T cells (TRM) that stay in place. These cells remember invading germs or cancer and quickly mount a response if that enemy reappears.

The preclinical findings,...

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